Table 3.

Summary of statistical tests to be conducted for hypotheses within specific aim 1.

Hypotheses	Outcome measure	Statistical tests
		Crude	Adjusted covariates
Veterans with PTEa will report poorer health than veterans with NTEb, TBIc only, and neither epilepsy nor TBI.	VR-12d Veteran health	2-tailed t test: VR-12 score; χ2 test: VR-12 ≤45; χ2 test: presence of comorbidity	Veteran age, sex, SESe, social support
Caregivers of veterans with PTE will report poorer health than caregivers of veterans with NTE, with TBI only, and neither epilepsy nor TBI.	VR-12 Caregiver health	2-tailed t test: VR-12 score; χ2 test: VR-12 ≤45	CGf age, sex, SES, social support
Caregivers of veterans with PTE will higher burden than caregivers of veterans with NTE, with TBI only, and neither epilepsy nor TBI.	Zarit 12-item caregiver burden	2-tailed t test: Zarit score; χ2 test: Zarit score ≥16	CG age, sex, SES, social support, health, relationship to Veteran
Caregivers of veterans with PTE will report higher caregiving intensity than caregivers of veterans with NTE, with TBI only, and neither epilepsy nor TBI.	NACg caregiving intensity level	χ2 test: intensity category; χ2 test: intensity ≥4	CG age, sex, SES, social support, health, relationship to Veteran
Caregivers of veterans with PTE and associated comorbidities will report poorer health, higher burden, and higher caregiving intensity than caregivers of veterans with PTE without comorbidities and veterans with similar comorbidities (eg, depression and headache) but without epilepsy.	Modified O’Malley caregiver needs measure	2-tailed t test: number of unmet needs; χ2 test: presence of each unmet need	CG social support and SES

^aPTE: posttraumatic epilepsy.

^bNTE: nontraumatic epilepsy.

^cTBI: traumatic brain injury.

^dVR-12: veterans RAND-12.

^eSES: socioeconomic status.

^fCG: caregiver.

^gNAC: National Alliance for Caregiving.