Table 3. Adjusted Association of Baseline N-Terminal Pro–Brain Natriuretic Peptide (NT-proBNP) and Blood Pressure With Severity of Hypertensive Disorders of Pregnancy^a,b.

Measure	Adjusted OR (95% CI)
	No APO (n = 3182)	GH (n = 292)	Preeclampsia
			Term (≥37 wk; n = 182)	Preterm (<37 wk; n = 70)	With severe features (n = 136)
NT-proBNP, median (IQR), pg/mL	63.0 (41.0-95.0)	54.0 (36.0-89.0)	50.0 (33.0-76.0)	42.0 (29.0-72.0)	49.0 (31.5-74.0)
NT-proBNP, per doubling in value	1 [Reference]	0.86 (0.74-0.99)c	0.78 (0.66-0.93)c	0.71 (0.54-0.93)c	0.77 (0.63-0.93)c
NT-proBNP, per doubling in value, controlling for systolic blood pressure	1 [Reference]	0.89 (0.77-1.03)	0.80 (0.67-0.95)c	0.75 (0.57-0.99)c	0.80 (0.65-0.98)c

Abbreviations: APO, adverse pregnancy outcome; GH, antepartum gestational hypertension; OR, odds ratio.

^a Adjusted for age, race and ethnicity, body mass index, smoking, and aspirin use.

^b This characteristic is included in statistical models after a logarithm transformation (base, 2). ORs for log-transformed quantities are interpreted on the multiplicative scale.

^c P < .05.