Table 5.
Predictive biomarkers for HPD
| Biomarkers | Cancer types | Predictive effect on HPD | Ref |
|---|---|---|---|
| MDM2 family amplification | Not mentioned | Positive (4 in 6 patients, 67%) | 160 |
| EGFR mutation | Not mentioned | Positive (2 in 10 patients, 20%) | 160 |
| Elevated NLR | NSCLC | Positive | 153 |
| Elevated levels of LDH, ANC and CRP | Advanced gastric cancer | Positive | 161 |
| Ki67+ PD1+ Treg cells | Gastric cancer | Positive | 162 |
| CCR7- CD45RA-CD8+T memory cells | NSCLC | Negative | 153 |
| TIGIT+PD1+CD8+ T cells | NSCLC | Positive | 153 |