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. 2022 Jan 1;13(2):481–495. doi: 10.7150/jca.65012

Table 5.

Predictive biomarkers for HPD

Biomarkers Cancer types Predictive effect on HPD Ref
MDM2 family amplification Not mentioned Positive (4 in 6 patients, 67%) 160
EGFR mutation Not mentioned Positive (2 in 10 patients, 20%) 160
Elevated NLR NSCLC Positive 153
Elevated levels of LDH, ANC and CRP Advanced gastric cancer Positive 161
Ki67+ PD1+ Treg cells Gastric cancer Positive 162
CCR7- CD45RA-CD8+T memory cells NSCLC Negative 153
TIGIT+PD1+CD8+ T cells NSCLC Positive 153