Table 3.

Micronucleus test in the bone marrow of the rats that underwent bile duct ligation, treated or not with melatonin

Groups	MNPCE1 in 2000 PCE	Ratio PCE/NCE2
CO	4.0 ± 1.5	1.1 ± 0.2
CO + MLT	3.3 ± 1.0	1.1 ± 0.4
BDL	7.8 ± 1.3a	1.0 ± 0.6
BDL + MLT	6.8 ± 1.9	0.9 ± 0.5

¹MNPCE: Micronuclei in polychromatic erythrocytes.

²PCE/NCE ratio: Proportion of polychromatic erythrocytes/normochromatic erythrocytes.

^a P < 0.01: Significant increase in the bile duct ligation group in relation to the control and CO + melatonin groups. (Analysis of variance, Tukey test).

CO: Control; MLT: Melatonin; BDL: Bile duct ligation.