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. 2022 Jan 20;20:38. doi: 10.1186/s12951-021-01236-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — HUCMSCs-EVs protein abundance and their putative functions. A The ten most abundant hUCMSCs-EVs proteins determined by LC–MS/MS Analysis. B The ten most abundant hUCMSCs-EVs proteins were arranged and exhibited by the histogram. C The proportion of the ten most abundant hUCMSCs-EVs proteins in total miRNAs. D The ratio of each of the ten most abundant hUCMSCs-EVs proteins in total miRNAs. E The top 30 most enriched GO terms for these proteins by GO analysis. F The top 15 most enriched pathways for these proteins by KEGG pathway analysis