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. Author manuscript; available in PMC: 2022 Jan 20.
Published in final edited form as: Curr Opin Pharmacol. 2020 Nov 27;56:46–51. doi: 10.1016/j.coph.2020.09.016

Figure 2.

Figure 2

Schematic of possible lynx1 action on transition states of nAChRs.

(a) nAChR (green) states.

(b) nAChR with lynx1 present (2L03, ribbon).

(c) Reduced cholinergic drive at synapses with lynx1-bound nAChR complexes.