TABLE 1.
Clinical characteristics of neonates with NEC (June-July 1998)
| Patient | Sexb | Date of birth (day/mo) | Gestational age (wk) | Birth wt (g) | Length of stay (days) | Type of feeding | Start of feeding (day/mo) | Date of onset (day/mo) | NEC stagec |
E. sakazakii culturea
|
Date of death (day/mo) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood | Stomach | Anus | |||||||||||
| 1 | M | 05/05 | 27 | 850 | 120 | Alfaré | 19/06 | 29/06 | I | − | + | − | |
| 2 | F | 21/05 | 31 | 1,930 | 64 | Prématil | 05/06 | 06/06 | II | − | NP | NP | |
| 3 | M | 22/05 | 27 | 995 | 42 | Alfaré | 26/06 | 01/07 | III | NP | NP | NP | 02/07 |
| 4d | M | 22/05 | 27 | 965 | 63 | Alfaré | 21/06 | 24/06 | III | +e | − | + | 23/07 |
| 5 | F | 23/05 | 29 | 815 | 74 | Alfaré | 11/06 | 03/07 | II | NP | NP | NP | |
| 6 | F | 08/06 | 28 | 1,200 | 89 | Alfaré | 12/06 | 30/06 | III | − | − | −f | |
| 7 | M | 10/06 | 28 | 1,100 | 80 | Alfaré | 16/06 | 19/06 | III | − | − | +g | |
| 8 | F | 14/06 | 27 | 590 | 111 | Alfaré | 20/07 | 23/07 | II | − | + | +g | |
| 9 | F | 16/06 | 31 | 1,350 | 47 | Alfaré | 22/06 | 03/07 | I | − | + | +e | |
| 10 | F | 16/06 | 32 | 1,490 | 39 | Alfaré | 19/06 | 25/06 | I | NP | NP | NP | |
| 11 | M | 26/06 | 32 | 1,290 | 43 | Alfaré | 27/06 | 03/07 | I | − | − | + | |
| 12 | M | 03/07 | 30 | 1,550 | 32 | Prématil | 06/07 | 07/07 | I | − | − | − | |
a
NP, not performed; −, negative; +, positive.
b
F, female; M, male.
c
I, suspected disease; II, definite disease; III, advanced disease.
d
Twin brother of patient 3.
e
Two morphologically different E. sakazakii isolates were found.
f
Enterobacter cloacae, Escherichia coli, and Enterococcus faecalis were isolated.
g
Isolate was not stored and thereby was not available for molecular typing.