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Inhibition of EZH2 increased the sensitivity of pancreatic cancer to albumin-bound paclitaxel. (A) Dual staining of SOX8, EZH2 and SPARC and (B) Statistical Analysis. (C) SPARC expression in Panc-1-SOX8 cells treated with UNC1999. (D) Picture of tumors and (E) tumor volume. (F) IHC straining of EZH2/SPARC of primary tumor and (G) Statistical Analysis. (H) Working model.
