Table 2.
Overall grade (modified glucksberg/MAGIC/Minnesota) | Modified glucksberg criteria (keystone aGvHD consensus) (66) | MAGIC criteria (69) | Minnesota criteria (68) | IBMTR criteria (67) | Overall grade (IBMTR) |
---|---|---|---|---|---|
0 | No organ involvement | 0 | |||
I | Skin stage 1 or 2, without liver/GI involvement | A | |||
II | Skin stage 3, and/or liver stage 1, and/or GI stage 1 | Skin stage 2, and/or liver stage 1 or 2, and/or GI stage 1 or 2 | B | ||
III | Liver stage 2 or 3, and/or GI stage 2–4 | Liver stage 2 or 3, and/or GI stage 2 or 3 | Liver stage 2–4, and/or GI stage 2 or 3 | Skin stage 3, and/or liver stage 3, and/or GI stage 3 | C |
IV | Skin stage 4, and/or liver stage 4 | Skin stage 4, and/or liver stage 4, and/or GI stage 4 | Skin stage 4, and/or GI stage 4 | Skin stage 4, and/or liver stage 4, and/or GI stage 4 | D |
Adapted with permission from Schoemans et al. (70).
aGvHD, acute graft versus host disease; GI, gastrointestinal; IBMTR, International blood and marrow transplant registry; MAGIC, Mount sinai acute GvHD international consortium.