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. 2022 Jan 6;9:784377. doi: 10.3389/fped.2021.784377

Table 2.

Assessment of aGvHD assessment: overall severity grading according to the different classifications.

Overall grade (modified glucksberg/MAGIC/Minnesota) Modified glucksberg criteria (keystone aGvHD consensus) (66) MAGIC criteria (69) Minnesota criteria (68) IBMTR criteria (67) Overall grade (IBMTR)
0 No organ involvement 0
I Skin stage 1 or 2, without liver/GI involvement A
II Skin stage 3, and/or liver stage 1, and/or GI stage 1 Skin stage 2, and/or liver stage 1 or 2, and/or GI stage 1 or 2 B
III Liver stage 2 or 3, and/or GI stage 2–4 Liver stage 2 or 3, and/or GI stage 2 or 3 Liver stage 2–4, and/or GI stage 2 or 3 Skin stage 3, and/or liver stage 3, and/or GI stage 3 C
IV Skin stage 4, and/or liver stage 4 Skin stage 4, and/or liver stage 4, and/or GI stage 4 Skin stage 4, and/or GI stage 4 Skin stage 4, and/or liver stage 4, and/or GI stage 4 D

Adapted with permission from Schoemans et al. (70).

aGvHD, acute graft versus host disease; GI, gastrointestinal; IBMTR, International blood and marrow transplant registry; MAGIC, Mount sinai acute GvHD international consortium.