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. 2022 Jan 6;9:762370. doi: 10.3389/fpubh.2021.762370

Table 2.

(A) Multivariable logistic regression analysis for AAC in patients with CKD Stages 1–4. (B) Multivariable logistic regression analysis for CVC in patients with CKD Stages 1–4.

Characteristic OR 95%CI P
(A)
Age, per 1 year increase 1.08 1.06–1.10 <0.001
Gender, male vs. female 0.63 0.39–1.01 0.05
BMI, per 1 kg/m2 1.01 0.96–1.06 0.838
History of CVD, yes vs. no 1.76 1.20–2.59 0.004
Tobacco use, yes vs. no 1.73 1.10–2.70 0.03
Hemoglobin, per 1 g/L increase 0.99 0.98–1.00 0.003
Serum albumin, per 1 g/L increase 1.03 1.00–1.07 0.08
24–h urine protein, per 1 natural log increase (g/24 h) 1.09 0.95–1.25 0.22
Hypertension, yes vs. no 1.90 1.08–3.32 0.03
Diabetes, yes vs. no 1.87 1.33–2.65 <0.001
Triglyceride, per 1 natural log increase (mmol/L) 1.01 0.73–1.40 0.95
Cholesterol, per 1 natural log increase (mmol/L) 0.72 0.43–1.20 0.21
LDL–C, per 1 natural log increase (mmol/L) 1.89 1.11–3.21 0.02
eGFR, per 1 ml/min/1.73m2 increase 1.003 0.995–1.010 0.50
Serum uric acid, per 1 umol/L increase 1.002 1.000–1.004 0.02
Serum calcium, per 1 mmol/L increase 0.61 0.21–1.77 0.36
Serum phosphorus, per 1 natural log increase (mmol/L) 0.98 0.43–2.24 0.97
IPTH, per 1 natural log increase (pg/ml) 0.94 0.72–1.23 0.65
Calcium–free phosphorus binder, yes vs. no 0.75 0.44–1.26 0.27
Active vitamin D, yes vs. no 0.60 0.33–1.10 0.10
(B)
Age, per 1 year increase 1.125 1.10–1.15 <0.001
Gender, male vs. female 1.022 0.63–1.66 0.93
BMI, per 1 kg/m2 1.02 0.97–1.08 0.46
History of CVD, yes vs. no 1.56 1.05–2.33 0.03
Tobacco use, yes vs. no 1.10 0.69–1.76 0.69
Hemoglobin, per 1 g/L increase 1.00 0.99–1.01 0.80
Serum albumin, per 1 g/L increase 0.96 0.92–1.00 0.03
24–h urine protein, per 1 natural log increase (g/24 h) 1.01 0.87–1.16 0.95
Hypertension, yes vs. no 0.77 0.47–1.25 0.29
Diabetes, yes vs. no 1.00 0.68–1.46 0.98
Triglyceride, per 1 natural log increase (mmol/L) 1.30 0.92–1.85 0.14
Cholesterol, per 1 natural log increase (mmol/L) 1.21 0.70–2.09 0.51
LDL–C, per 1 natural log increase (mmol/L) 0.42 0.24–0.73 0.002
eGFR, per 1 ml/min/1.73m2 increase 0.994 0.985–1.003 0.19
Serum uric acid, per 1 umol/L increase 0.998 0.997–1.000 0.08
Serum calcium, per 1 mmol/L increase 2.37 0.75–7.53 0.14
Serum phosphorus, per 1 natural log increase (mmol/L) 1.14 0.45–2.85 0.79
IPTH, per 1 natural log increase (pg/ml) 0.86 0.65–1.15 0.31
Calcium–free phosphorus binder, yes vs. no 0.97 0.59–1.58 0.89
Active vitamin D, yes vs. no 1.30 0.78–2.17 0.31

BMI, body mass index; CVD, cardiovascular disease; LDL–C, low–density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate, IPTH: intact parathyroid hormone.