Table 2.

Summary of the principal cellular subsets significantly and differentially abundant between COV and CT group individuals.

Inferior in COV-Group compared to CT-group
Cellular subsets	Frequency/AbsN
CD4+ HLADR+ CD38+ → activated CD4+ T cells	AbsN
CD4+ CD45RAneg CCR4neg CCR10neg CCR6neg CD27+ CXCR3+ CD127+ → Th1 central memory	Frequency
CD8+ CD127+ CD27+ CCR10+ CD45RA+ → atypical naïve CD8	Frequency
CD4+ CXCR3+ CD127+ CD27+ CCR10+ → atypical Th1 central memory	Frequency
CD4+ CD28+ CXCR3+ PD-1+ → Tfh1 PD-1+	Frequency
CD4+ CD28+ CD45RAneg CD127+ CXCR3+ → memory Th1	Frequency
CD4+ CD28+ CD45RAneg CD127+ CXCR3+ CCR6+ → memory Th1/Th17	Frequency
Neutrophils	Frequency
Superior in COV-Group compared to CT-group
Cellular subsets	Frequency/AbsN
Tfh1 ICOS+ PD-1+ → cTfh1 ICOS+ PD-1+	Frequency
CD80+/CD86+ B cells → activated B cells	Frequency/AbsN
CD80/CD86+ CD38+ CD27int CD138int B cells → plasmablasts	Frequency
CD80/CD86+ CD27+ CD138+ CD38+ PD-1+ B cells → PD-1+ plasma cells	Frequency
Eosinophils	Frequency/AbsN
Follicular DC	Frequency/AbsN
CD14+ CD3+ CD62L+ → unconventional double positive	Frequency
CD3neg CD14neg CD62L+ CD16+ CD123+ CD1c int → atypical DC	Frequency

At the top of the table are the cell subsets with a frequency or AbsN lower in the COV group compared to the CT group, while the bottom part of the table has the subsets with a frequency or AbsN greater in the COV group compared to the CT group. The left column gives the cellular subsets and their most representative markers. The right column indicates if a difference between groups was observed in terms of subsets’ frequency or absolute numbers.