Bozkurt 2020.
Study characteristics | ||
Methods | Randomised controlled trial | |
Participants | Preterm infants of birth weight ≤ 1250 g Zekai Tahir Burak Maternity Teaching Hospital, Istanbul, Turkey (2016 to 17) |
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Interventions | Delayed progressive enteral feeding (minimal enteral nutrition for 5 days after birth, 110 infants) versus earlier progressive enteral feeding (within 48 hours, 109 infants), with feed volumes advanced by 20 to 25 mL/kg/d until 150 mL/kg/d feed volume achieved Infants received expressed maternal milk (first choice) or formula or both |
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Outcomes |
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Notes | Mean gestation at birth: 27weeks' Mean birth weight: 963 g Further information courtesy of Dr Ozlem Bozturk (March 2020) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer‐generated |
Allocation concealment (selection bias) | Low risk | Sequentially‐numbered sealed opaque envelopes |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Unmasked |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Unmasked |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Complete cohort assessed |
Selective reporting (reporting bias) | Low risk | Unlikely |
Other bias | Low risk | No evidence baseline imbalance |