Figure 5. Interactions between Aβ-m and a graphene quantum dot.

(A) Structure of the GQD used in the simulations. Time evolution of (B) distance between each Aβ residue and the GQD and (C) secondary structure of Aβ-m peptides from a typical DMD simulation trajectory. (D) Snapshots of the interaction process shown in B and C. The GQD was represented by sticks and Aβ-m was shown as cartoon with the N-terminus indicated by a sphere. (E) β-sheet propensity of each Aβ-m residue in the absence and presence of the GQD. (F) Secondary structure contents of Aβ-m with and without the GQD. (G) Binding frequency of each Aβ-m residue with the GQD.