Table 2.

Summary of somatic variants in sequenced samples

Sample*	Number of somatic SNVs	Number of Mutations/ Mb	Annotation of Somatic SNVs			Number of shared somatic SNVs	% of shared SNVs
			Exonic		Intronic
			Total	Non-synonymous
1084_P0	4056	1.35	37	25	854	228	5.6%
1084_T0	6070	2.02	77	59	1950		3.8%
1249_P0	4142	1.38	39	27	897	387	9.3%
1249_T0	1120	0.37	13	10	288		34.6%
1494_P0	3433	1.14	22	11	783	262	7.6%
1494_T0	1271	0.42	18	11	392		20.6%
1524_P0	4771	1.59	39	23	1090	281	5.9%
1524_T0	2841	0.95	37	23	840		9.9%
065_P0	3857	1.29	38	24	897	–	–
098_P0	5637	1.88	47	28	1356	–	–

* T0 tumour, P0 plasma, * Patients with breast cancer - 1084, 1249, 1494 and 1524; patients with benign tumours - 065 and 098