Table 3.
The association between RC value and DR
Factors | Univariate model | Multivariate model | ||||
---|---|---|---|---|---|---|
OR | 95%CI | P-value | OR | 95%CI | P-value | |
Age, per10y increase | 1.221 | 1.051–1.418 | 0.009** | 1.002 | 0.981–1.022 | 0.880 |
Diabetes duration, per 1y increase | 1.357 | 1.184–1.555 | 0.000** | 1.072 | 1.036–1.110 | 0.000** |
DPN, yes or no | 1.561 | 1.067–2.284 | 0.022 | 1.201 | 0.770–1.873 | 0.419 |
Anitihypertensive drugs, yes or no | 0.6 | 0.458–0.994 | 0.046 | 1.062 | 0.666–1.690 | 0.800 |
SBP, per10mmHg increase | 1.16 | 1.043–1.289 | 0.006* | 1.004 | 0.992–1.018 | 0.498 |
FBG, per 1 mmol/L increase | 1.04 | 0.976–1.108 | 0.228 | |||
HbA1c per1% increase | 1.078 | 0.971–1.197 | 0.159 | |||
Uric acid per 1 μmol/l increase | 1.00 | 0.998–1.001 | 0.61 | |||
TC, per 1 mmol/L increase | 1.367 | 1.145–1.632 | 0.000** | 0.936 | 0.731–1.198 | 0.598 |
TG, per 1 mmol/L increase | 1.087 | 0.995–1.187 | 0.064 | |||
HDL-C, per 1 mmol/L increase | 1.315 | 0.676–2.556 | 0.42 | |||
LDL-C, per 1 mmol/L increase | 1.007 | 0.793–1.279 | 0.956 | |||
eGFR, per10-1-1 (ml/min/1.73m2) increase | 0.93 | 0.844–1.026 | 0.147 | |||
mAlb > 30 mg/24 h, yes or no | 1.003 | 1.001–1.005 | 0.003* | 1.334 | 0.814–2.185 | 0.252 |
TyG-index per1 increase | 1.393 | 1.095–1.772 | 0.007 | 0.766 | 0.554–1.059 | 0.106 |
RC, per 1 mmol/L increase | 6.823 | 4.011–11.609 | 0.000** | 5.623 | 2.996–10.556 | 0.000** |
NLR per1 increase | 1.801 | 1.310–2.477 | 0.000** | 1.598 | 1.121–2.279 | 0.01* |
Abbreviations: DR diabetic retinopathy, DPN diabetic peripheral neuropathy, BMI body mass index, SBP systolic blood pressure, FBG Fasting blood glucose, HbA1c glycosylated hemoglobin, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, APOA apolipoprotein A, APOB apolipoprotein B, eGFR estimated glomerular filtration rate, TyG-index triglyceride glucose index, SBP systolic blood pressure, UA Uric acid, NLR Neutrophil–Lymphocyte ratio, TyG-index triglyceride glucose index, mAlb microalbuminuria
Notes: Binary Logistic Regression Analysis.*P < 0.05, **P < 0. 001