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. 2022 Jan 20;21:12. doi: 10.1186/s12944-021-01621-7

Table 3.

The association between RC value and DR

Factors Univariate model Multivariate model
OR 95%CI P-value OR 95%CI P-value
Age, per10y increase 1.221 1.051–1.418 0.009** 1.002 0.981–1.022 0.880
Diabetes duration, per 1y increase 1.357 1.184–1.555 0.000** 1.072 1.036–1.110 0.000**
DPN, yes or no 1.561 1.067–2.284 0.022 1.201 0.770–1.873 0.419
Anitihypertensive drugs, yes or no 0.6 0.458–0.994 0.046 1.062 0.666–1.690 0.800
SBP, per10mmHg increase 1.16 1.043–1.289 0.006* 1.004 0.992–1.018 0.498
FBG, per 1 mmol/L increase 1.04 0.976–1.108 0.228
HbA1c per1% increase 1.078 0.971–1.197 0.159
Uric acid per 1 μmol/l increase 1.00 0.998–1.001 0.61
TC, per 1 mmol/L increase 1.367 1.145–1.632 0.000** 0.936 0.731–1.198 0.598
TG, per 1 mmol/L increase 1.087 0.995–1.187 0.064
HDL-C, per 1 mmol/L increase 1.315 0.676–2.556 0.42
LDL-C, per 1 mmol/L increase 1.007 0.793–1.279 0.956
eGFR, per10-1-1 (ml/min/1.73m2) increase 0.93 0.844–1.026 0.147
mAlb > 30 mg/24 h, yes or no 1.003 1.001–1.005 0.003* 1.334 0.814–2.185 0.252
TyG-index per1 increase 1.393 1.095–1.772 0.007 0.766 0.554–1.059 0.106
RC, per 1 mmol/L increase 6.823 4.011–11.609 0.000** 5.623 2.996–10.556 0.000**
NLR per1 increase 1.801 1.310–2.477 0.000** 1.598 1.121–2.279 0.01*

Abbreviations: DR diabetic retinopathy, DPN diabetic peripheral neuropathy, BMI body mass index, SBP systolic blood pressure, FBG Fasting blood glucose, HbA1c glycosylated hemoglobin, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, APOA apolipoprotein A, APOB apolipoprotein B, eGFR estimated glomerular filtration rate, TyG-index triglyceride glucose index, SBP systolic blood pressure, UA Uric acid, NLR Neutrophil–Lymphocyte ratio, TyG-index triglyceride glucose index, mAlb microalbuminuria

Notes: Binary Logistic Regression Analysis.*P < 0.05, **P < 0. 001