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. 2022 Jan 4;7(2):1595–1601. doi: 10.1021/acsomega.1c06085

Table 1. Interaction Outcomes of Coffee with Other Food Materialsa.

material polyphenols synergistic attributes antagonistic/additive attributes ref
cinnamon cinnamic acid, coumarin proanthocyanidins LOXi RSA, RSA,b LOXib (7)
ginger caffeic acid RSA, LOXib RSA,b LOXi (8)
willow: Salix myrsinifolia salicin/salicylic glycosides LOXi, OH RSA, CHEL, FRAP (9)
willow: Salix purpurea LOXi, CHEL, OH RSA, FRAP (9)
willow: Salix myrsinifolia and Salix purpurea LOXi, FRAP RSA (10)
cardamom protocatechuic acid, vanillic acid, p-coumaric acid, ferulic acid FRAP, CHEL, SOD, LOXi, XOi CHEL,b SOD,b OH, LOXib (11)
coconut catechin, epicatechin, vanilic acid, gallic acid RSA, RSAb LOX (12)
whole meal wheat flour trans- and cis-ferulic acids XOi   (13)
chili pepper capcaicin RSA, OH, SOD, SASA RSA,b CHEL, OH,b FRAP (14)
cocoa catechins, epicatechins, anthocyanins, and procyanidins RSA   (15)
Ginkgo biloba L., Scutellaria baicalensis, and quercetin-3-O-rutinoside hydroxycinnamic acid, caffeoylquinic acid, etc. H2O2 AChE (17)
N/A α-tocopherol vs chlorogenic acid   antioxidant capacity (23)
N/A α-tocopherol vs caffeic acid/ferulic acid antioxidant capacity   (23)
a

LOXi, lipoxygenase inhibition activity; RSA, radical scavenging activity; CHEL, chelating power; OH, OH• scavenging assay; FRAP, ferric reducing antioxidant power; XOi, xanthine oxidase inhibiting activity; SOD, superoxide dismutase-like activity; SASA, superoxide anion scavenging activity; H2O2, hydrogen peroxide scavenging activity; AchE, acetylcholinesterase inhibition.

b

Outcome after in vitro digestion.