TABLE 1.
Demographics and clinical characteristics of the study cohort
| Patients with normal QTc | Patients with long QTc | P valuea | |
|---|---|---|---|
| Number | 410 | 208 | |
| Male gender | 251 (61.2%) | 136 (65.3%) | .312 |
| Age (years) | 59.2 ± 12.3 | 60.1 ± 13.4 | .028 |
| Body mass index (kg/m2) | 28.8 ± 6.5 | 32.8 ± 8.6 | <.001 |
| Hypertension | 253 (61.7%) | 155 (74.5%) | .001 |
| Diabetes mellitus | 105 (25.6%) | 96 (46.2%) | <.001 |
| Hyperlipidemia | 192 (46.8%) | 130 (62.5%) | <.001 |
| Heart failure | 48 (11.7%) | 61 (29.3%) | <.001 |
| Coronary artery disease | 139 (33.9%) | 81 (38.9%) | .216 |
| Tumor type | |||
| RCC | 190 (46.3%) | 71 (34.1%) | .003 |
| CML | 112 (27.3%) | 63 (30.3%) | .438 |
| AML | 7 (1.7%) | 11 (5.3%) | .124 |
| ALL | 20 (4.9%) | 21 (10.1%) | .014 |
| Thyroid | 31 (7.6%) | 22 (10.6%) | .206 |
| GIST | 19 (4.6%) | 9 (4.3%) | .862 |
| Lung | 31 (7.6%) | 11 (5.3%) | .288 |
Abbreviations: ALL, acute lymphocytic leukemia; AML, acute myeloid leukemia; GIST, gastrointestinal stromal tumor; CML, chronic myeloid leukemia; RCC, renal cell carcinoma.
a
P value for comparisons between all patients with normal QTc vs all patients with long QTc interval.