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. Author manuscript; available in PMC: 2022 Jan 20.
Published in final edited form as: Clin Cancer Res. 2020 Apr 24;26(15):4018–4030. doi: 10.1158/1078-0432.CCR-19-3416

Figure 4.

Figure 4.

Organization of immune cells and frequency of TLS. A, IHC stains shows diffuse distribution of T cells (CD3+ and CD8+) in UPS with no B cells (CD20+) present. In ERMS and ARMS, T cells (CD3+ and CD8+) cluster together with B cells (CD20+) forming TLS. TAMS (CD163+) are diffusely distributed in all sarcomas. CSF1R appears stronger in UPS and ARMS. PD-L1 is present through all sarcomas but stronger in UPS. B, The frequency of TLS in each sarcoma subtype varies and originates from different anatomical sites.