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. 2021 Dec 27;11(1):57. doi: 10.3390/antiox11010057

Figure 2.

Figure 2

The role of S-nitrosylation in IRI. S-nitrosylation causes a functional change of the nitrosylated target protein, which tends to inhibit or promote severe progression of IRI. This suggests that inhibition of SNO-proteins in the orange box should be considered for more efficient use of NO donors or GSNOR inhibitors for the treatment of IRI.