Table 4.
Antioxidant activity of compounds toward DPPH-derived free radicals.
| Entry | Compound | DPPH | ||
|---|---|---|---|---|
| Scavenging at 100 µM, % | Scavenging at 1mM, % | IC50, μM | ||
| 1 | Trolox | 93.4 ± 0.5 | 92.2 ± 0.5 | 11.4 ± 1.0 |
| 2 | Ascorbic acid | - | - | 16.2 ± 0.7 |
| 3 | CGP37157 | 9.6 ± 1.8 | 24.3 ± 1.4 | - |
| 4 | rac-3a [19] | 15.1 ± 3.4 [19] | 37.4 ± 3.8 [19] | - |
| 5 | (rac,R)-3b [19] | 8.7 ± 5.1 [19] | 30.7 ± 3.9 [19] | - |
| 6 | R-6 | 10.30 ± 1.10 | 26.7 ± 1.3 | - |
| 7 | S-6 | 8.47 ± 2.42 | 25.3 ± 1.5 | - |
| 8 | (S,S)-7a | 10.9 ± 3.5 | 30.3 ± 1.6 | - |
| 9 | (S,R)-7b | 8.46 ± 3.8 | 32.0 ± 1.7 | - |
| 10 | (R,S)-7c | 13.6 ± 3.8 | 35.9 ± 1.9 | - |
| 11 | (R,R)-7d | 8.66 ± 3.0 | 23.3 ± 3.5 | - |
Data are expressed as means ± SEM of three different experiments in duplicate.