Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 22;10(1):8. doi: 10.3390/biomedicines10010008

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CD276 and TIM-3 expression positively correlates with the poor prognosis of UC. GEO dataset (GSE32894) was analyzed to determine the clinical significance of UC. (A) CD276 (C) HAVCR2 (TIM-3) expression was grouped by early pathological stage (I + II) and late-stage (III + IV). (B,D) Overall survival of 224 UC patients was grouped by lower and higher (B) CD276 (D) TIM3 expression using the median value as a cut-off. Kaplan-Meier survival analysis was performed. (E) Multivariate Cox regression survival plot of 224 patients with UC was grouped by lower (n = 111) and higher (n = 113) CD276 expression using the median value as the cut-off. (F) Results of the CD276 multivariate analysis. *** p < 0.001.