TABLE 1.
Sources of the intestinal samples from 28 Australian patients diagnosed with IS, and subsequent PCR results using primers specific for B. aalborgi and B. pilosicoli 16S rRNA and nox genes
| Sourcea | Sex, ageb | Symptoms and/or endoscopic findings | Biopsy location | Histologic findings and/or clinical histologyc | Results for 16S rRNA and nox PCRs
|
|
|---|---|---|---|---|---|---|
| B. aalborgi | B. pilosicoli | |||||
| Perth, WA | F, 35 | 12-yr ulcerative-colitis disease history; inactive at time of biopsy | Cecum | IS | + | − |
| Transverse colon | Minor changes | + | − | |||
| Ascending colon | IS | + | − | |||
| Hepatic flexure | IS | + | − | |||
| Splenic flexure | IS | + | − | |||
| Sigmoid | IS | + | − | |||
| Rectum | IS | + | − | |||
| Perth, WA | F, 41 | Diarrhea; O/E ulcers | Colon at 130 cm | IS; inflammation | + | − |
| Colon at 80 cm | IS; active inflammation | + | − | |||
| Rectum | IS; active inflammation | + | − | |||
| Perth, WA | F, 49 | Diarrhea | Duodenum | Negative | − | − |
| Random colon | IS; lymphocyte aggregates | + | − | |||
| Perth, WA | F, 53 | Polyps | Cecum | IS | + | − |
| Transverse colon | IS | + | − | |||
| Descending colon | IS | + | − | |||
| Hepatic flexure | IS | + | − | |||
| Sigmoid colon | IS | + | − | |||
| Rectum | IS | + | − | |||
| Perth, WA | F, 56 | Altered bowel habit | Rectum | IS; lymphocyte aggregates | + | − |
| Perth, WA | M, 25 | Epigastric pain; lower abdominal cramps | Gastric antrum | Negative | − | − |
| Gastroesophageal junction | Inflammation | − | − | |||
| Colon at 80 cm | IS; minor changes | + | − | |||
| Colon at 35 cm | IS; inflammation | + | − | |||
| Rectum | IS; minor lymphocyte aggregates | + | − | |||
| Perth, WA | M, 29 | Right iliac fossa pain | Appendix | IS | + | − |
| Appendix | IS | + | − | |||
| Perth, WA | M, 35 | Anemia | Gastric antrum | Negative | − | − |
| Duodenum | Negative | − | − | |||
| Terminal ileum | Negative | − | − | |||
| Right colon | IS; lymphocyte aggregates | + | − | |||
| Left colon | IS; lymphocyte aggregates | + | − | |||
| Rectum | Minor changes | − | − | |||
| Rectal polyp | Adenoma | − | − | |||
| Perth, WA | M, 36 | HIV+; homosexual | Liver | Negative | − | − |
| Sigmoid | IS; minor changes; lymphocyte aggregates | + | − | |||
| Anal canal | Inflammation; fibrosis; no dysplasia | − | − | |||
| Perth, WA | M, 43 | Not recorded | Rectum | IS; active inflammation; CMV | + | − |
| Perth, WA | M, 81 | Gastritis | Gastric antrum | Gastritis | − | − |
| Cecum | IS; minor changes | + | − | |||
| Ascending colon | IS; minor changes | + | − | |||
| Transverse colon | IS | + | − | |||
| Splenic flexure | IS | + | − | |||
| Descending colon | IS | + | − | |||
| Sigmoid colon | IS | + | − | |||
| Rectum | IS | + | − | |||
| Denmark, WA | F, 52 | Polyp | Transverse colon | IS | + | − |
| Bridgetown, WA | M, 27 | Rectal bleeding; pain; proctitis | Ileum | Normal | − | − |
| Descending colon | IS | + | − | |||
| Right colon | IS | + | − | |||
| Rectum | Proctitis | − | − | |||
| Port Headland, WA | M, 27 | Rectal bleeding | Rectum | IS; minor changes | + | − |
| Rectum | IS | + | − | |||
| Geraldton, WA | M, 35 | Ulcerative proctitis | Rectum | IS; lymphocyte aggregates | + | − |
| Kalgoorlie, WA | M, 36 | Diarrhea; congestion | Rectum | IS; minor changes; lymphocyte aggregates | + | − |
| Darwin, NT | F, 25 | Rectal bleeding | Sigmoid colon | IS; inflammation; tubular adenoma formation; mild epithelial atypia | + | − |
| Darwin, NT | F, 47 | 1-yr history of intermittent and mild right iliac fossa pain | Colon | IS; metaplastic polyps | + | − |
| Darwin, NT | F, 47 | Irritable bowel | Cecum | IS; associated mild increase in eosinophils within lamina propria | + | − |
| Darwin, NT | M, 35 | Bloody diarrhea; diverticulitis? | Colon | IS | + | − |
| Darwin, NT | M, 45 | Rectal bleeding | Rectum | IS | + | − |
| Melbourne, Vic | F, 51 | Not recorded | Colon | IS | + | − |
| Wyndham, WA | M, 36 | Trauma-ischemia | Appendix | IS | + | + |
| Transverse colon | IS | + | − | |||
| Darwin, NT | M, 47 | Not recorded | Mid-transverse colon | IS; hyperplastic polyps | + | + |
| Perth, WA | M, 30 | HIV+; diarrhea | Sigmoid colon | IS; mild nonspecific inflammatory changes | − | + |
| Darwin, NT | F, 16 | Appendicitis | Appendix | IS; acute appendicitis | − | + |
| Perth, WA | F, 67 | Diarrhea | Ascending colon | Minor changes | − | − |
| Transverse colon | Possibly IS; minor changes | − | − | |||
| Sigmoid colon | Adenoma | − | − | |||
| Perth, WA | M, 38 | Acute appendicitis? | Appendix | IS | − | − |
a
NT, Northern Territory; Vic, Victoria.
b
F, female; M, male. Ages are given in years.
c
CMV, cytomegalovirus.