Table 5.

Early treatment response and early occurrence of nephrotoxicity according to each cutoff AUC on day 2 in patients with high/moderate-risk and low-risk MRSA infections.

Pharmacokinetics Parameter		Early Treatment Response, No. of Patients (%)
		High/Moderate-Risk MRSA Infections		Low-Risk MRSA Infections
a. Early treatment response
AUC on day 2 (µg·h/mL)	<400	19/51 (37.3%)	reference	37/73 (50.7%)	reference
	≥400	29/54 (53.7%)	p = 0.091	62/82 (75.6%)	p = 0.001
b. Early nephrotoxicity
AUC on day 2 (µg·h/mL)	<600	1/100 (1.0%)	reference	2/147 (1.4%)	reference
	≥600	2/5 (40.0%)	p = 0.005	2/8 (25.0%)	p = 0.013

AUC: area under the concentration–time curve.