Table 2.
Genes | APP | BACE1 | PSEN1 | PSEN2 | |
---|---|---|---|---|---|
Survival | |||||
2 days | ↓ | ↑↑ | ↔ | ↑↑ | |
7 days | ↑ | ↔ | ↔ | ↔ | |
30 days | ↑ | ↔ | ↔ | ↔ |
Expression: ↑ increase; ↑↑ increase; ↓ decrease, ↔ oscillation around control values. Genes: APP-amyloid protein precursor, BACE1-β-secretase, PSEN1-presnilin 1, PSEN2-presenilin 2.