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. 2022 Jan 6;11(1):123. doi: 10.3390/antiox11010123

Figure 2.

Figure 2

meso-Dihydroguaiaretic acid (MDGA) reduces reactive oxygen species (ROS) generation in activated human neutrophils. Dihydrorhodamine 123 (DHR123)- or luminol-incubated neutrophils were incubated with DMSO (0.1%, as control) or MDGA (0.1–10 μM), and activated by fMLF (0.1 μM) or PMA (10 nM). ROS production was detected by flow cytometry or chemiluminometer. The mean fluorescence intensity of (A,B) was quantified and shown in (C,D), respectively. The AUC value of (E,F) was quantified and shown in (G,H), respectively. The values are shown as the mean ± S.E.M. (n = 6). # p < 0.05 vs. non-stimulated control; * p < 0.05 vs. stimulated control.