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. 2022 Jan 6;11(1):123. doi: 10.3390/antiox11010123

Figure 5.

Figure 5

meso-Dihydroguaiaretic acid (MDGA) inhibits human neutrophil CD11b expression and adhesion. (A) After incubation with DMSO (0.1%, black line) or MDGA (1, 3, and 10 μM, red line), human neutrophils were stimulated by fMLF (green line). The mean fluorescence intensity was quantified and shown in the right panel. (n = 5). (B) Neutrophils were first stained with Hoechst 33342 and then incubated with DMSO (0.1%, as control) or MDGA (1, 3, and 10 μM) before fMLF activation. Stimulated neutrophils were co-cultured with bEnd.3 cells and the numbers of adherent neutrophils were calculated using microscopy. Bar, 100 μm. Adherent neutrophils were measured in the right panel. (n = 6). All data are shown as the mean ± S.E.M. * p < 0.05 vs. activated control.