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. 2022 Jan 6;11(1):123. doi: 10.3390/antiox11010123

Figure 8.

Figure 8

meso-Dihydroguaiaretic acid (MDGA) attenuates lipopolysaccharide (LPS)-induced neutrophilic lung inflammation. BALB/c mice were intraperitoneally treated with DMSO or MDGA (30 mg/kg) for 1 h, and LPS was administered intratracheally for 6 h. Mice were divided into four groups: vehicle, MDGA only, LPS only, and LPS with MDGA groups. (A) HE stains of the lung. (B) An assay to evaluate lung MPO activity. (C) Images of Ly6G and MPO in lung sections. Immunofluorescence staining of 4’,6-diamidino-2-phenylindole (DAPI), lymphocyte antigen 6 complex locus G6D (Ly6G), histone H3 (citH3) (D), elastase (E), and 4-HNE (F) in lung sections. Data are illustrated as the mean ± S.E.M. (n = 6). * p < 0.05 vs. the LPS group.