Figure 7.

Effects of Efavirenz in human primary hepatocytes, hepatic stellate cells and Kupffer cells. Relative mRNA expression levels of inflammatory and fibrogenic genes in hepatocytes (A), hepatic stellate cells (B) and Kupffer cells (C) (RT-PCR). Data were normalized versus the housekeeping gene β-actin (n = 3). Data (mean ± SEM) were calculated as percentage of control (untreated cells) and analyzed by one-way ANOVA multiple comparison test followed by a Newman–Keuls test (* p < 0.05, ** p < 0.01 versus the respective solvent).