α7AchR	alpha-7 nicotinic receptor
2-AG	2-arachidonoylglycerol
AEA	anandamide
ATP	adenosine triphosphate
cAMP	cyclic adenosine monophosphate
CB1	cannabinoid receptor type 1
CBD	cannabidiol
CFA	Complete Freund’s adjuvant
CGRP	calcitonin gene-related peptide
CNS	central nervous system
CSD	cortical spreading depression
CSF	cerebrospinal fluid
DR	nucleus raphe dorsalis
DRG	dorsal root ganglion
GLUT R	glutamate receptors
GPR35	G protein-coupled receptor 35
5-HT1B/1D	5-hydroxytryptamine receptors
IDO	indoleamine 2,3-dioxygenase
IS	inflammatory soup
KMO	kynurenine 3-monooxygenase
KP	tryptophan-kynurenine metabolic pathway
KYNA	kynurenic acid
KYNU	kynureninase
LC	locus coeruleus
miRs	microRNAs
NGF	nerve-growth factor
NI	neurogenic inflammation
NK1	neurokinin 1
NKA	neurokinin A
nNOS	neuronal nitric oxide synthase
NO	nitric oxide
NPY	neuropeptide Y
NRM	nucleus raphe magnus
NSAIDs	nonsteroidal anti-inflammatory agents
NT	neurotransmitter
PAC1R	pituitary adenylate cyclase 1 receptor
PACAP	pituitary adenylate cyclase-activating polypeptide
PAG	the periaqueductal grey matter
PEA	palmitoylethanolamide
pERK	phosphorylated extracellular signal-regulated kinase
PKA	protein kinase A
PKC	protein kinase C
PLC	phospholipase C
PPE	plasma protein extravasation
SP	substance P
TACR1	tachykinin Receptor 1
TG	trigeminal ganglion
THC	tetrahidrokannabinol
TNC	caudal trigeminal nucleus
TNFα	tumor necrosis factor alpha
TRPV1	transient receptor potential vanilloid-1 receptor
TS	trigeminal system
VIP	vasoactive intestinal peptide
VPAC1/2	vasoactive intestinal peptide receptor 1/2