Figure 3.

Illustrative presentation of the pupil changes. (a). Normal pupil presentation in healthy rats ((a), white letter). (b). Persisting mydriasis (i.e., at 24 h post-injury) as effect of cauterization of the three episcleral veins. (c). Persisting mydriasis (i.e., at 24 h post-injury) as effect of cauterization of the three episcleral veins. (d). Counteraction of the previously persisting mydriasis (i.e., throughout 24 h post-injury) as effect of cauterization of the three episcleral veins upon BPC 157 therapy. (e). Upon distilled water eye therapy, unchanged presentation of continuously persisting mydriasis (i.e., throughout 24 h post-injury) as effect of cauterization of the three episcleral veins. Regular effect of cauterization of the three episcleral veins ((b,c), black letters), persisting mydriasis, illustration at 24 h post-injury (arrows), and effect of therapy application, BPC 157 (mydriasis counteraction) ((d), black letter) ((b)→(d)) or distilled water eye drops ((c), black letter) (persisted mydriasis) ((c)→(e)) (at 1 min after therapy). A similar effect was noted with all BPC 157 regimens. USB microscope camera Veho Discovery VMS-004 Deluxe. A total of 6 rats/group/interval.