Figure 9.

Cauterization of the three episcleral veins induced a decrease in retinal outer nuclear layer thickness, means ± SD, µn, at the first post-operative day and at the end of the fourth and sixth post-injury week. Counteracting effect of BPC 157 medication daily regimen, prophylactic (a–c) or curative (d–f) (gray bars, light gray bars µg-regimen, dark gray bars ng-regimen (0.4 µg/eye, 0.4 ng/eye; 10 µg/kg, 10 ng/kg) given locally as eye drops in each eye (a,d), intraperitoneally (last application at 24 h before sacrifice) (b,e) or per-orally in drinking water (0.16 µg/mL, 0.16 ng/mL, 12 mL/rat until the sacrifice, first application given intragastrically) (c,f)), started prophylactically (immediately before glaucoma surgery) or as curative treatment (at 24 h after glaucoma surgery). Controls (white bars) simultaneously received an equal volume of distilled water (two drops/eye), saline intraperitoneal application (5 mL/kg) or per-oral drinking water (12 mL/day/rat. A total of 6 rats/group/interval. * p < 0.05, at least, vs. control.