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. 2022 Jan 13;11(1):153. doi: 10.3390/antiox11010153

Table 1.

Different types of bio-macromolecule delivery vehicles of ascorbic acid.

Carrier Material Technology Protective Effect Encapsulation Efficiency Reference
Microcapsules Sodium alginate/gum Arabic Spray drying Thermal stability temperature of ascorbic acid is increased to 188 °C. >90% [91]
Xyloglucan Spray drying After 60 days of storage at room temperature, the retention of ascorbic acid is around 90%. ~96% [92]
Gum Arabic/rice starch Spray drying The retention of ascorbic acid is around 81.3% after 90 days of storage at 21 °C. ~99.7% [98]
Gelatin/pectin Complex coacervation With low hygroscopicity and high thermal stability. 23.7% to 94.3% [15]
Gelatin/acacia Complex coacervation The retention of ascorbic acid is around 44% and 80% after 30 days of storage at 37 °C and 20 °C, respectively. ≥97% [93]
Liposome Palm fat/chitosan Microfluidic technique After 30 days, retained 98.58% and 97.62% of ascorbic acid at 4 °C and 20 °C, respectively. ~ 96.6% [6]
Polyglyceryl monostearate Spray chilling The system can inhibit the Maillard reaction between milk proteins and ascorbic acid. ~94.2% [98]
Milk fat globule membrane-derived phospholipids Microfluidic technique After 7 weeks at 4 °C and 25 °C, ascorbic acid in liposomes retained 67% and 30%, respectively. ~26% [97]
W/O/W emulsions Gelatin/tetraglycerin monolaurate condensed ricinoleic acid ester/decaglycerol monolaurate Homogenization The half-life for W/O/W emulsions containing 30% ascorbic acid at 4 °C was about 24 days. ≥90% [99]
Soybean oil/tetraglycerin condensed ricinoleic acid ester/gelatin Homogenization and microchannel emulsification The ascorbic acid exhibited 80% retention after 10 days storage at 4 °C. >85% [100]