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. 2021 Dec 27;10(1):53. doi: 10.3390/biomedicines10010053

Figure 1.

Figure 1

Signaling pathways associated with the ghrelin receptor. The ghrelin receptor employs Gαq/11 signaling, Gαi/o signaling, and Gα12/13 signaling, followed by β-arrestin recruitment. Each G-protein/β-arrestin is associated with physiological effects. AC: adenylyl cyclase; AMPK: adenosine-monophosphate-activated protein kinase; ERK: extracellular signal-regulated kinase; mTOR: mammalian target of rapamycin; p-: phosphorylated-; RhoA: Ras homolog family member A; SRE: serum response element. Created with BioRender.com.