MND	motor neuron disease
HSP	Hereditary Spastic Paraplegia
IAHSP	Infantile-onset ascending hereditary spastic paralysis
JPLS	Juvenil Primary Lateral Sclerosis
ALS	Amyotrophic Lateral Sclerosis
JALS	Juvenil Amyotrophic Lateral Sclerosis
ALS2	Amyotrophic Lateral Sclerosis type 2
GEF	guanine exchange factor
GTPases	guanosine triphosphatases
RCC1	Regulator of Chromosome Condensation 1
RLD	RCC1-like domain
DH	central B cell lymphoma homology
PH	pleckstrin homology
VPS9	vacuolar protein-sorting 9
MORN	membrane occupation and recognition nexus
IDR	intrinsically disordered region
Ran	Ras-related nuclear
LMN	lower motor neurons
GRIP1	glutamate receptor-interacting protein 1
AMPA	a-amino-3-hydroxy-5-methylisoxazole-4-propio-nate
ALS2(−;−):	ALS2 knockout homozygous
SOD1	Cu/Zn-superoxide dismutase
IGF1	insulin-like growth factor
EEA1	early endosome-associated protein
PAK1	p21-activated kinase