ALS |
amyotrophic lateral sclerosis |
ANLS |
astrocyte–neuron lactate shuttle |
ATP |
adenosine triphosphate |
ARE |
antioxidant response element |
D2R |
dopamine D2 receptor |
DAMPs |
damage-associated molecular patterns |
DAT |
dopamine transporter |
G6PH |
glucose 6-phosphate dehydrogenase |
GSH |
reduced form of glutathione |
GSSG |
oxidized form of glutathione |
HCAR1 |
hydroxycarboxylic acid receptor 1 |
HO-1 |
heme oxygenase 1 |
iPSC |
induced pluripotent stem cell |
Keap1 |
Kelch-like enoyl-CoA hydratase-associated protein 1 |
l-DOPA |
l-3,4-dihydroxyphenylalanine |
LPS |
lipopolysaccharide |
MAPK |
mitogen-activated protein kinase |
MCT |
monocarboxylate transporter |
NET |
norepinephrine transporter |
NADPH |
nicotinamide adenine dinucleotide phosphate |
NMDA |
N-methyl-D-aspartate |
NF-κB |
nuclear factor-κB |
NO |
nitric oxide |
NOS |
nitric oxide synthase |
NRF-1 and NRF-2 |
nuclear respiration factors 1 and 2 |
Nrf2 |
nuclear factor erythroid 2 p45 subunit-related factor 2 |
GSSG |
oxidized form of glutathione |
PGC-1α |
peroxisome-proliferator-activated γ co-activator-1α |
PPAR-γ |
peroxisome proliferator-activated receptor γ |
PPP |
pentose–phosphate pathway |
PSD-95 |
postsynaptic density protein 95 |
ROS |
reactive oxygen species |
SERT |
serotonin transporter |
SIRT-1 |
sirtuin 1 |
TCA |
tricarboxylic acid |
TFAM |
mitochondrial transcription factor A |
TLR4 |
Toll-like receptor 4 |
VTA |
ventral tegmental area |
xCT |
cystine/glutamate antiporter |