Table 2.

Description of the whole sample across follow-up times (N:47). Statistically significant differences (p-value ≤ 0.05) are underlined in bold.

	T0		T3		p-Value
	Mean ± SD	Median (Min to Max)	Mean ± SD	Median (Min to Max)
CDAI (Crohn’s Disease Activity Index score, CD patients)	288.09 (60.73)	286.5 (168 to 414)	209.68 (57.64)	204 (137 to 371)	<0.0001
Mayo score (UC patients)	13.64 (2.78)	14 (7 to 19)	8.64 (2.75)	9 (4 to 14)	<0.0001
GM-CSF (pg/mL)	1.29 ± 5.13	0 (0 to 32.37)	1 ± 4.84	0 (0 to 32.05)	0.14
IFN-α (pg/mL)	7.87 ± 4.65	9.05 (0 to 17.45)	7.38 ± 4.66	9.45 (0 to 14.65)	0.90
IFN-γ (pg/mL)	44.23 ± 120.39	0 (0 to 662.92)	41.85 ± 110.29	0 (0 to 662.92)	0.60
TNFα (pg/mL)	8.83 ± 36.19	0 (0 to 232.08)	6.54 ± 32.23	0 (0 to 217.51)	0.07
TNFα (detectable)	6 (12.50)		6 (12.50)		--
CRP (mg/dL)	1.59 ± 2.06	0.64 (0.05 to 7.85)	0.74 ± 1.19	0.15 (0.05 to 5.29)	<0.01
IL-10 (pg/mL)	39.31 ± 73.16	30.56 (0 to 441.55)	41.24 ± 68.24	31.06 (0 to 431.89)	0.69
IL-12 (pg/mL)	53.54 ± 196.61	0 (0 to 1145.63)	44.03 ± 176.04	0 (0 to 1134.84)	0.42
IL-17A (pg/mL)	3.44 ± 5.92	2.3 (0 to 36.23)	3.35 ± 5.56	2.61 (0 to 34.69)	0.82
IL-2 (pg/mL)	0.48 ± 3.35	0 (0 to 23.19)	0.52 ± 3.57	0 (0 to 24.72)	0.95
IL-4 (pg/mL)	20.81 ± 37.44	5.18 (0 to 215.53)	18.52 ± 36.48	3.39 (0 to 228.54)	0.51
IL-5 (pg/mL)	9.84 ± 34.55	0 (0 to 199.9)	6.59 ± 23.85	0 (0 to 147.07)	0.10
IL-6 (pg/mL)	3.63 ± 18.02	0 (0 to 106.12)	1.01 ± 6.98	0 (0 to 48.38)	0.37
IL-9 (pg/mL)	15.72 ± 50.43	0 (0 to 299.73)	15.09 ± 47.5	0 (0 to 290.69)	0.75
IL-1β (pg/mL)	9.88 ± 21.29	1.78 (0 to 126.75)	23.28 ± 110.19	2.37 (0 to 765.91)	0.67
Folate (ng/mL)	6.87 ± 5.59	4.95 (1.9 to 28)	8.14 ± 6.63	6.4 (1.7 to 28)	0.05
Vitamin B12 (pg/mL)	267.75 ± 141.19	244.5 (69 to 682)	245.98 ± 114.12	220 (83 to 566)	0.03
Vitamin D (ng/mL)	21.59 ± 10.29	19.45 (4.8 to 65.5)	20.21 ± 8.03	20.2 (4.6 to 46.4)	0.12