Table 3.

Drug likeness parameters and derived for 3, 5, 6, 9, and 11 ligands.

Cpd.	3	5	6	9	11
HBD	1	2	4	3	2
HBA	8	9	8	7	8
Log.P	2.83	3.21	2.25	2.42	2.74
Log.S	−5.53	−6.13	−5.73	−4.26	−5.11
V	0	0	0	0	0
TPSA	105.5	132.48	157.05	112.93	116.5
%ABS	72.6	73.83	66.7	70.03	68.8
Mutagenic	none	none	none	low	none
Tumorigenic	none	none	none	high	none
Reproductive Effective	none	none	none	high	none
Irritant	none	none	none	high	none