Table 1.

Principal features of EVs.

General Characteristics of EVs
Types of EVs	Different Classification by	Process Mediated	EVs Used as
Exosomes	Size	Physiological/homeostasis (beneficial effects)	Biomarker (in clinical prognosis or diagnosis)
Microvesicles/Microparticles	Morphology	Pathological effect: chronic inflammatory diseases (CKD, diabetes, hypertension, peripheral vascular disease, heart failure, and CKD).	Therapeutic target
Apoptotic bodies	Biochemical composition		Therapeutic tool
Small or large EVs	Release mechanism