Figure 1.

Effects of 3,3-dimethyl-1-butanol (DMB) treatment on blood pressure, organ morphology, and proteinuria in control (CTR) and imiquimod (IMQ) mice. (A) Systolic blood pressure (SBP) as determined by tail-cuff plethysmography; (B) morphology data as organ weigh/tibia length ratios; and (C) proteinuria in CTR, CTR-group treated with DMB (CTR-DMB), IMQ, and IMQ-group treated with DMB (IMQ-DMB). The data are expressed in a means ± SEM format. Tail SBP and proteinuria were tested by two-way ANOVA with the Tukey’s multiple comparison test. The morphological variables were tested with one-way ANOVA and Tukey’s post hoc test, or Kruskal–Wallis test with Dunn’s multiple comparisons. ** p < 0.01 in comparison with CTR; ^## p < 0.01 in comparison with IMQ.