Table 5.

Lymphocyte subpopulations in peripheral blood at SARS-CoV-2 vaccination by serological conversion after vaccination.

Lymphocyte Subpopulations	All Pts		p	Pts after alloHCT
	Pts with Seroconversion N	Pts without Seroconversion N		Pts with Seroconversion N	Pts without Seroconversion N	p
	77	7		53	6
Median (range) of lymphocyte count in blood (G/L)	1.36 (0.33–6.67)	1.13 (0.79–3.77)	0.69	1.38 (0.33–6.67)	1.32 (0.79–3.77)	0.89
Median (range) of B-cell count in blood (G/L)	0.21 (0.00–1.11)	0.01 (0.00–0.35)	0.014	0.22 (0.0–1.11)	0.07 (0.0–0.35)	0.038
Median (range) percentage of B cells in blood (%)	13.5 (0.1–41.0)	1.5 (0.0–10.0)	<0.001	14.5 (1.40–41.0)	4.50 (0.04–10.00)	<.001
Median (range) of T-cell count in blood (G/L)	0.89 (0.23–5.86)	1.08 (0.42–2.90)	0.66	0.87 (0.23–5.86)	1.03 (0.42–2.89)	0.83
Median (range) percentage of T cells in blood (%)	66.9 (23.0–95.9)	76.8 (53.3–95.9)	0.098	65.9 (23.0–95.9)	23.95 (13.90–38.50)	0.27
Median (range) of CD4+ T-cell count in blood (G/L)	0.23 (0.04–0.73)	0.21 (0.1–0.64)	0.92	0.22 (0.04–0.73)	0.21 (0.09–0.64)	0.64
Median (range) percentage of CD4+ T cells in blood (%)	28.0 (9.4–70.1)	25.8 (13.9–38.5)	0.76	28.0 (9.4–70.1)	23.95 (13.9–38.5)	0.57
Median (range) of CD8+ T-cell count in blood (G/L)	0.61 (0.11–5.34)	0.64 (0.24–2.21)	0.80	0.57 (0.11–5.34)	0.64 (0.24–2.21)	0.72
Median (range) percentage of CD8+ T cells in blood (%)	70.4 (27.9- 91.1)	64.1 (56.8–82.3)	0.66	70.3 (27.9–91.1)	70.2 (56.8–82.3)	0.98
Median (range) of NK-cell count in blood (G/L)	0.13 (0.02–0.71)	0.15 (0.04–0.37)	0.50	0.12 (0.02–0.71)	0.17 (0.12–0.37)	0.10
Median (range) percentage of NK cells in blood (%)	15.2 (2.1–54.3)	12.8 (3.9–45.8)	0.99	13.9 (2.1–54.3)	18.7 (8.1–45.8)	0.47

Pts, patients; HCT, hematopoietic stem cell transplantation; alloHCT, allogeneic hematopoietic stem cell transplantation; IS, immunosuppressive; TCI, Transplant Conditioning Intensity; CNI, calcineurin inhibitor; NA, not applicable.