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. 2022 Jan 8;14(2):308. doi: 10.3390/cancers14020308

Table 4.

Bias-adjusted results from the parsimonious Cox models with combined CD163+ TAM marker.

Predictor Hazard Ratio (*) LL 95% CI UL 95% CI p-Value
Histological Grade 2 vs. 1 2.17 0.99 4.76 0.056
Histological Grade 3 vs. 1 2.74 1.19 6.31 0.021
HR- vs. HR+ Hormone Tx Compliant 1.52 0.77 3.01 0.233
HR+ Hormone Tx Non-Compliant vs. Compliant 2.67 1.35 5.28 0.007
Node Positive vs. Negative 1.86 1.12 3.09 0.019
Tumor Size 2–5 cm vs. <2 cm 1.75 1.02 3.00 0.046
Tumor Size >5 cm vs. <2 cm 2.81 1.48 5.33 0.002
Low vs. High Median Cancer-to-CD163+ NND
AND Low Average Number of communicating CD163+ TAMs
2.29 1.14 4.63 0.024
High vs. Low Average Number of communicating CD163+ TAMs
AND High or Low Median Cancer-to-CD163+ NND
2.47 1.42 4.29 0.002

(*) Bootstrap-based optimistic bias-adjusted hazard ratio.