Table 2.
Simple linear regression analyses with APPLIQue as the dependent variable, n = 74.
| Independent Variables | Unstandardized | Standardized | p-Value |
|---|---|---|---|
| Coefficient β (95% CI) | Coefficient β | ||
| Patient data | |||
| Age (year) | −0.198 (−0.400 to 0.003) | −0.225 | 0.053 |
| PD duration | −0.141 (−0.336 to 0.054) | −0.167 | 0.155 |
| Patient gender (ref = male) | −3.935 (−6.744 to −1.125) | −0.313 | 0.007 |
| Partner | 4.017 (0.603 to 7.431) | 0.266 | 0.022 |
| Dwelling place (home vs. nursing home) | −1.252 (−4.195 to 1.691) | −0.099 | 0.399 |
| Hoehn and Yahr stage | 1.200 (−2.106 to 4.507) | 0.085 | 0.472 |
| ADL independency (S&E) | −0.022 (−0.126 to 0.082) | −0.05 | 0.674 |
| Home health care (yes) | 0.950 (−2.427 to 4.328) | 0.066 | 0.577 |
| Cognition, MMSE | −0.088 (−0.324 to 0.148) | −0.09 | 0.458 |
| Cognitive impairment (dichotomized 0–23 vs. 24–30) | −4.271 (−7.135 to −1.407) | −0.337 | 0.004 |
| Depressive symptoms (GDS-30) | −0.065 (−0.295 to 0.166) | −0.069 | 0.578 |
| Depression (dichotomized 0–9 vs. 10–30) | −0.561 (−3.549 to 2.428) | −0.046 | 0.709 |
| Motor function (UPDRS III total score) | 0.039 (−0.053 to 0.132) | 0.099 | 0.399 |
| Non-motor symptomatology (NMSS total score) | 0.036 (0.008 to 0.065) | 0.292 | 0.012 |
| Hallucinations (NMSS item 13) | 0.206 (−0.209 to 0.621) | 0.116 | 0.325 |
| Hallucinations (dichotomized 0 vs. ≥ 1) | 1.368 (−1.531 to 4.267) | 0.11 | 0.350 |
| Delusions (NMSS item 14) | 0.089 (−0.546 to 0.723) | 0.033 | 0.781 |
| Delusions (dichotomized 0 vs. ≥ 1) | 1.167 (−2.364 to 4.698) | 0.077 | 0.512 |
CI, confidence interval; PD, Parkinson’s disease; APPLIQue, the Alzheimer’s Patient Partners Life Impact Questionnaire (score range 0–25, higher = worse); q1–q3, first and third quartiles; ref, reference category; HY, Hoehn and Yahr staging scale (score range I-V, higher = worse); ADL, activities of daily living; S&E, Schwab and England ADL scale (score range 0–100, higher = better); MMSE, Mini-mental state examination (score range 0–30, higher = better); NMSS, Non-Motor Symptoms Scale (0–360, higher = worse); GDS-30, Geriatric Depression Scale (score range 0–30, higher = worse); UPDRS III, Unified PD Rating Scale, part III = motor examination (score range 0–108, higher = worse). Bold p-values are statistically significant at p < 0.05.