Table 1.

Relevant PD-L1 scores assessment in malignant tumors.

PD-L1 Scores	Analysis Assessment	References
Tumor Cell (TC)	TC (%) = [Number of PD-L1-stained tumor cells/Total number of viable tumor cells] × 100%	[18,22,23]
Tumor-Proportion Score (TPS)	TPS (%) = [Number of PD-L1-stained tumor cells/Total number of viable tumor cell] × 100%	[18,22,24]
Immune-Cell Score (IC)	IC (%) = [Area of tumor infiltrated by PD-L1-stained immune cells/Total tumor area] × 100%	[18,22,25]
Immune Cells Present (ICP)	ICP (%) = Percentage of tumor area occupied by any PD-L1 positive immune cell staining.	[25]
Combined Positive Score (CPS)	CPS = [Number of PD-L1-stained cells (tumor cells, lymphocytes and macrophages)/Total number of viable tumor cells] × 100	[18,22,23]