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Fluctuations of the stress hormones cortisol and estradiol levels in the saliva of a volunteer during the testing period of a 4-mg nicotine pack. The upper limits of the physiological norms of both hormones, taking into account the time of day, gender and age of the subject, are 2.2 ng/mL and 4.6 pg/mL for cortisol and estradiol, respectively.
