Table 6.

Cross-sectional interrelationship between BMI, leptin, proinflammatory cytokines, and oxidative stress parameters.

Parameter	BMI		Leptin		IL-6		TNF-α		ROS		GPx
	r	p	r	p	r	p	r	p	r	p	r	p
Type I cancer (G1–G2 endometrioid)
BMI
Leptin	0.874	<0.001
IL-6	0.540	<0.001	0.895	<0.001
TNF-α	0.175	0.072	0.331	0.087	0.419	0.006
ROS	0.458	0.010	0.655	<0.001	0.844	<0.001	0.276	0.089
GPx	0.109	0.354	0.089	0.680	−0.547	0.006	−0.228	0.473	−0.493	0.007
SOD	0.053	0.918	0.154	0.675	−0.546	0.021	−0.364	0.073	−0.430	0.010	0.280	0.105
Type II cancer (non-endometrioid and G3 endometrioid)
BMI
Leptin	0.876	<0.001
IL-6	−0.144	0.394	0.168	0.210
TNF-α	0.165	0.138	−0.392	0.328	0.410	0.060
ROS	−0.250	0.129	0.178	0.249	0.695	0.003	0.109	0.570
GPx	−0.198	0.215	−0.071	0.508	−0.234	0.231	−0.197	0.144	0.105	0.684
SOD	−0.157	0.453	−0.163	0.218	−0.305	0.178	0.239	0.106	−0.760	0.004	0.348	0.075

Abbreviations: r, correlation factor; EC, endometrial cancer; BMI, body mass index; IL, interleukin; TNF, tumor necrosis factor; ROS, reactive oxygen species; GPx, glutathione peroxidase; SOD, superoxide dismutase. p-value was calculated by Pearson’s or Spearman’s correlation analysis and was considered significant if it was less than 0.05 (bold value).