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Tumor suppressor/oncoprotein and EBV modulators in various cancers.
| Cancer | Tumor Suppressor/Oncoprotein | EBV Modulators |
|---|---|---|
| Burkitt’s lymphoma | c-Myc | EBNA-2 |
| EBV-encoded micro-RNAs | ||
| BHRF1 | ||
| Nasopharyngeal carcinoma | p53 | EBV-miR-BART5-3p |
| EBNA 3C | ||
| EBNA1 | ||
| LMP1 | ||
| EBNA2 | ||
| E-cadherin | LMP1 | |
| T-cell lymphoma | PD-L1 [74] | LMP1 |
| Gastric cancers | PTEN, CDKN2, CDH1, p15, p73, etc. | LMP2A |
| EBV-encoded microRNAs | ||
| Breast cancer | Nm23-H1 | EBNA 3C |
