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The αVβ3 integrin binder shows tumor homing in 786-O RCC tumor-bearing mice. Tumor homing of (A) the IR800-coupled αVβ3 binder conjugate, (B) the non-binding control conjugate, or the (C) carboxylate dye control in 786-O tumor-bearing mice as detected by near-infrared imaging. The color scale shows arbitrary near-infrared fluorescence units as displayed by the Pearl® Imager software. A representative image from each treatment group is shown (n = 3).
