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. 2022 Jan 14;11(2):282. doi: 10.3390/cells11020282

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Confocal microscope images presenting characteristic markers—collagen II, aggrecan, and SOX-9 after the 12-day culturing of chondrocytes on Cur_WPI biomaterials and polystyrene (PS). Collagen I was also visualized to determine chondrocyte dedifferentiation towards fibroblast-like cells. Nuclei emitted blue fluorescence, while evaluated markers gave green fluorescence (visible green fluorescence in the structure of biomaterial was emitted by WPI); magnification 200×, scale bar equals 70 μm.