ALL |
acute lymphoblastic leukemia |
AML |
acute myeloid leukemia |
Antp |
Drosophila Antennapedia protein |
BCL |
B cell lymphoma |
BRCA |
Breast Cancer-associated Protein |
CAF |
chromatin assambly complex |
CAK |
CDK-activating kinase |
CDK |
cyclin-dependent kinase |
CDKI |
cyclin-dependent kinase inhibitor |
Cip/Kip |
CDK interacting protein/Kinase inhibitory protein |
CLL |
chronic lymphocytic leukemia |
CPP |
cell penetrating peptide |
CR |
complete response |
CRC |
colorectal cancer |
DLT |
dose-limiting toxicity |
DSB |
double-strand breaks |
EGFR |
epidermal growth factor receptor |
EMT |
epithelial-mesenchymal transition |
HCC |
hepatocellular carcinoma |
HNSCC |
head and neck squamous cell carcinoma |
HPV |
human papillomavirus |
IC50
|
half maximal tolerated dose |
ICB |
immune checkpoint blockade |
IFN |
Interferon |
LCSC |
lung cancer squamous cell |
M phase |
mitosis phase |
MCL |
mantle cell lymphoma |
MM |
multiple myeloma |
MTD |
maximum tolerated dose |
NHL |
non-Hodgkin’s lymphoma |
NPC |
nasopharyngeal carcinoma |
NSCLC |
non-small cell lung cancer |
OS |
overall survival |
OSCC |
oral squamous cell carcinoma |
PDK1 |
3-phosphoinositide-dependent protein kinase 1 |
PDX |
patient derived xenograft |
PFS |
Progression-Free Survival |
PPI |
protein-protein interactions |
PR |
partial response |
pRb |
phosphorylated retinoblastoma protein |
PROTAC |
proteolysis targeting chimera |
P-TEFb |
positive transcription elongation factor b |
Rb |
retinoblastoma protein |
RP2D |
recommended phase II dose |
R-point |
restriction point |
RNA Pol II |
RNA Polymerase II |
S phase |
synthesis phase |
SCLC |
Small-cell lung cancer |
SLL |
small lymphocytic lymphoma |
Ser/Thr |
serine/threonine |
SR |
stable disease |
T-ALL |
T cell acute lymphoblastic leukemia |
TGF |
Transforming Growth Factor |
TK1 |
Thymidine Kinase 1 |
TRAIL |
TNF-related apoptosis-inducing ligand |