Table 3.
Association between variables and upstage (invasive at surgery). Results from univariate and multivariate logistic regression analyses.
| Variable | Level | Upstage/Tot (%) | Univariate Analysis | Multivariate Analysis 1 | ||||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p-Value | OR | 95% CI | p-Value | |||
| Overall | - | 32/295 (10.8) | - | - | - | - | - | - |
| Age at Mammotome biopsy | +1 year | 0.94 | 0.90–0.99 | 0.018 | 0.95 | 0.90–1.00 | 0.068 | |
| Biopsy needle | 8G + 7G | 7/45 (15.6) | Ref. | - | - | Ref. | - | - |
| 11G + 10G | 25/245 (10.2) | 0.62 | 0.25–1.53 | 0.30 | 0.77 | 0.29–2.06 | 0.60 | |
| Missing | 0/5 | |||||||
| Post biopsy residual disease | No | 3/128 (2.3) | Ref. | - | - | Ref. | - | - |
| Yes | 29/167 (17.4) | 8.76 | 2.60–29.4 | <0.001 | 7.14 | 1.58–32.2 | 0.011 | |
| Post biopsy residual lesion size | +1 × log2 (mm) | 1.76 | 1.26–2.46 | <0.001 | 0.96 | 0.58–1.58 | 0.87 | |
| Number of cores | +1 | 0.98 | 0.91–1.05 | 0.53 | 0.98 | 0.90–1.05 | 0.53 | |
| Disease only in cores with microcalcifications | No | 24/132 (18.2) | Ref. | - | - | Ref. | - | - |
| Yes | 7/138 (5.1) | 0.24 | 0.10-0.58 | 0.002 | 0.33 | 0.13-0.83 | 0.018 | |
| Missing | 1/25 | |||||||
1 Twenty-nine patients with at least one missing value among independent variables were excluded from the model. Goodness of fit statistics: McFadden’s R-Square = 0.16; AIC = 174.6; −2 Log Likelihood = 160.6.